The psychoactivity of cannabis made all its varieties illegal, including hemp, which does not have this property.
The “high feeling” is due to THC (tetrahydrocannabinol), which is only one cannabinoid. However, most cannabinoids aren’t psychoactive but provide medicinal effects.
The second prevalent cannabinoid in this plant is cannabidiol (CBD)which can be derived from cannabis strains with low THC content, like Charlotte’s Web, for therapeutic use.
Cannabis is especially effective in the treatment of pain. As soon as CBD enters the bloodstream, it is attached to the cannabinoid receptors in the peripheral nerves and blocks the pain signals from reaching the brain.
This process also involves beta-caryophyllene, another non-psychoactive cannabinoid, which has a different molecular structure than most other cannabinoids. It soothes inflammation and blocks neural pain reception, and is also found in cinnamon, black pepper, basil, and oregano.
A study conducted at the University of Michigan study found that the use of medical cannabis to manage chronic pain reduces the need for opioid painkillers:
“Patients using medical marijuana to control chronic pain reported a 64 percent reduction in their use of more traditional prescription pain medications…