High BP Drug Could Treat Skin Cancer

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The findings are scheduled to be presented at the American Society for Pharmacology and Experimental Therapeutics annual meeting during the Experimental Biology 2017 meeting being held from April 22-26 in Chicago.

Carvedilol’s cancer-fighting properties were discovered when a former graduate student in Huang’s lab was studying whether carvedilol and similar beta blockers might increase cancer risk.

The student inadvertently tested carvedilol’s ant-icancer effect rather than its ability to promote cancer, finding that carvedilol surprisingly showed some protective effects against skin cancer.

The researchers then conducted experiments with cell cultures and mice to see if carvedilol could prevent skin cancer caused by ultraviolet-B (UVB), the portion of sunlight that tends to damage the skin’s top epidermal layers and plays a key role in skin cancer development.

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