A prescription weight-loss medication can decrease the urge to use opiates such as oxycodone, according to a recent study.
The researchers from the University of Texas Medical Branch at Galveston found that the drug, lorcaserin, reduced the use and craving for the opioid oxycodone in preclinical studies. Most of the treatments available to reduce opiate misuse work by occupying opioid receptors in the brain. If someone were to take an opiate while on these treatments, they would not feel the signature euphoria as strongly.
However, a person’s drug-taking environment is a powerful cue that can condition someone to anticipate the experience of taking of the drug; this is called cue reactivity.