The researchers found that carvedilol exhibited a protective effect in cultured mouse skin cells exposed to UVB and in hairless mice given the drug after UVB exposure.
The experiments showed that carvedilol acted by protecting cells against the cancer-causing DNA damage and cell death produced by UVB.
Hairless mice exposed to UVB and given carvedilol showed decreases in both the severity and number of tumours that developed compared to those not given carvedilol.
The mouse studies also showed that carvedilol delayed skin tumour formation more than sunscreen.
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